Recombinant CD147 Antibody / Emmprin / Basigin

This MAb recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.

Product Specifications

CAS Number

9000-83-3

Specifications

Flow cytometry: 1-2ug/million cells, Immunofluorescence: 1-3 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL

UniProt

P35613

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant full-length human BSG protein was used as the immunogen for the recombinant CD147 antibody.

Clonality

Recombinant Monoclonal

Isotype

IgG κ

Clone

BSG/6468R

Type

Recombinant

Applications

FACS, IF, IHC-P

Purity

Protein A/G affinity

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Aliquot the recombinant CD147 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This recombinant CD147 antibody is available for research use only.

Storage Conditions

Aliquot the recombinant CD147 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Applications Notes

Optimal dilution of the recombinant CD147 antibody should be determined by the researcher.

Location

Cytoplasm, Cell membrane

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