MRP1 Antibody / ABCC1
The two members of the large family of ABC transporters known to confer multidrug resistance in human cancer cells are the MDR1 P-glycoprotein and the multidrug-resistance protein MRP1. MRP1 is an integral membrane protein that contains an MDR-like core, an N-terminal membrane-bound region and a cytoplasmic linker, and it is expressed in various cerebral cells, as well as in lung, testis and peripheral blood.
Product Specifications
CAS Number
9007-83-4
Specifications
Flow cytometry: 1-2ug/million cells, Western blot: 2-4 µg/mL
UniProt
P33527
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length human ABCC1/MRP1 protein was used as the immunogen for the MRP1 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
MRP1/1343
Applications
ELISA, FACS, WB
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the MRP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This MRP1 antibody is available for research use only.
Storage Conditions
Aliquot the MRP1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the MRP1 antibody should be determined by the researcher.
Location
Cell membrane
Image Legend
SDS-PAGE analysis of purified, BSA-free MRP1 antibody (clone MRP1/1343) as confirmation of integrity and purity.
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