COL4A5 Antibody / Collagen IV
Type IV collagen is the major structural component of the glomerular basement membrane (GBM), forming a hexagonal network together with lamins, proteoglycans, and nestin. Deletions of the N-terminal regions of COL4A5 and COL4A6 were found in Xq22.3 chromosome deletion syndrome and were located in an end-to-end manner. This results in a phenotype characteristic of diffuse leiomyomatosis and Alport syndrome (DL-ATS) .
Product Specifications
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P29400
Host
Rabbit
Reactivity
Human
Immunogen
A recombinant fragment (within amino acids 1400-1685) of human COL4A protein was used as the immunogen for the COL4A5 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
COL4A5/9396R
Type
Recombinant
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the COL4A5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This COL4A5 antibody is available for research use only.
Storage Conditions
Aliquot the COL4A5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the COL4A5 antibody should be determined by the researcher.
Image Legend
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Colloidal Gold Conjugated Abrus precatorius Lectin (Jequirity Bean) -APA-, 15nm
![CDK1 Mouse Monoclonal Antibody [Clone ID: 8C5A6]](https://cdn.genprice.uk/products/937/68dd189a061270361e8fbde3/imageurl/am06437su-n.webp)