Recombinant IL3RA Antibody / Interleukin 3 Receptor alpha / CD123
CD123 is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5) . The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudo-autosomal region on chromosomes X or Y.
Product Specifications
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P26951
Host
Mouse
Reactivity
Human
Immunogen
A recombinant fragment of human IL3RA protein (within amino acids 26-171) was used as the immunogen for the recombinant IL3RA antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG2b κ
Clone
RIL3RA/9212
Type
Recombinant
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the recombinant IL3RA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This recombinant IL3RA antibody is available for research use only.
Storage Conditions
Aliquot the recombinant IL3RA antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the recombinant IL3RA antibody should be determined by the researcher.
Location
Cytoplasm, Cell membrane
Image Legend
Frequently Asked Questions
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