Recombinant CD44v6 Antibody
This antibody recognizes an epitope encoded by exon v6 on the variant portion of human CD44. The CD44 molecule belongs to a family of cellular adhesion molecules found on a wide range of normal and malignant cells in epithelial, mesothelial and hemopoiesis tissues. CD44 is a single gene with 20 exons, of which 10 are normally expressed to encode the basic CD44 (H-CAM) molecule. The additional 10 exons (v1 to v10) are only expressed by alternative splicing of the nuclear RNA. The expression of specific cell adhesion molecule CD44 splice variants has been reported to be associated with metastasis in certain human malignancies.
Product Specifications
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P16070
Host
Rabbit
Reactivity
Human
Immunogen
A recombinant fragment corresponding to the v3-v10 domain of human CD44 was used as the immunogen for the recombinant CD44v6 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
CD44V6/9400R
Type
Recombinant
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Aliquot the recombinant CD44v6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This recombinant CD44v6 antibody is available for research use only.
Storage Conditions
Aliquot the recombinant CD44v6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the recombinant CD44v6 antibody should be determined by the researcher.
Location
Cell membrane
Image Legend
Frequently Asked Questions
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