Fatty Acid Binding Protein 1 Antibody / FABP1
Fatty acid-binding proteins, designated FABPs, are a family of homologous cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epithelium (E-FABP, psoriasis-associated FABP, PA-FABP), striated muscle and heart (H-FABP, mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP or FABP1), myelin (M-FABP) and testis (T-FABP) . FABP1 (L-FABP) expression is modulated by developmental, hormonal, dietary and pharmacological factors, and is required for cholesterol synthesis and metabolism.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 2-4 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P07148
Host
Mouse
Reactivity
Human
Immunogen
A human recombinant FABP1 protein fragment (within amino acids 1-127) was used as the immunogen for the Fatty Acid Binding Protein 1 antibody.
Clonality
Monoclonal
Isotype
IgG2 κ
Clone
FABP1/4463
Applications
WB, IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Aliquot the Fatty Acid Binding Protein 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Fatty Acid Binding Protein 1 antibody is available for research use only.
Storage Conditions
Aliquot the Fatty Acid Binding Protein 1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the Fatty Acid Binding Protein 1 antibody should be determined by the researcher.
Location
Cytoplasm, Nucleus
Image Legend
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