SHBG Antibody / Sex Hormone Binding Globulin
Recognizes a protein of 45kDa, identified as SHBG. It functions as an androgen transport protein, but may also be involved in receptor-mediated processes. Each dimer binds one molecule of steroid. It is specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. SHBG regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P04278
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length human SHBG protein was used as the immunogen for the SHBG antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
SHBG/8175
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the SHBG antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This SHBG antibody is available for research use only.
Storage Conditions
Aliquot the SHBG antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the SHBG antibody should be determined by the researcher.
Location
Cytoplasm, Extracellular (Secreted)
Image Legend
Frequently Asked Questions
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