Growth Differentiation Factor 9 Antibody / GDF9
GDF9 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Growth factors synthesized by ovarian somatic cells directly affect oocyte growth and function. GDF9 is expressed in oocytes and is thought to be required for ovarian folliculogenesis. GDF9/6458 can be used in assays to detect oocyte expression and has been shown to neutralize GDF9 biological activity.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
O60383
Host
Mouse
Reactivity
Human
Immunogen
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
GDF9/6458
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the Growth Differentiation Factor 9 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Growth Differentiation Factor 9 antibody is available for research use only.
Storage Conditions
Aliquot the Growth Differentiation Factor 9 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the Growth Differentiation Factor 9 antibody should be determined by the researcher.
Location
Cytoplasm, Secreted
Image Legend
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