Blood Group Lewis y Antibody
This antibody recognizes a carbohydrate epitope present on tumor-associated Lewis Y antigen (Fucalpha1-2Galbeta1-4/3[Fucalpha1-3/4]GlcNAcbeta-) . Lewis Y is expressed in large bowel tumors and colorectal carcinomas. It may be useful in the classification of human renal and bladder tumors. The Lewis Y antigen has been evaluated as a clinical marker for the diagnosis and prognosis of cholangiocarcinoma, hepatocellular carcinoma and breast cancer.
Product Specifications
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL
Host
Rabbit
Reactivity
Human
Immunogen
H3396 cultured line established from a metastasis of a human breast adenocarcinoma was used as the immunogen for the Blood Group Lewis y antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
LWY/9243R
Type
Recombinant
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Aliquot the Blood Group Lewis y antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Blood Group Lewis y antibody is available for research use only.
Storage Conditions
Aliquot the Blood Group Lewis y antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the Blood Group Lewis y antibody should be determined by the researcher.
Location
Cell membrane, Cytoplasm, Extracellular
Image Legend
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Frequently Asked Questions
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