Nck2 Antibody / NCK adaptor protein 2
Adapter protein which associates with tyrosine-phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling. [UniProt]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000
UniProt
O43639
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide from human NCK adaptor protein 2 protein was used as the immunogen for the Nck2 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG
Clone
28N61
Type
Recombinant
Applications
WB
Purity
Affinity chromatography
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Limitations
This Nck2 antibody is available for research use only.
Storage Conditions
Store the Nck2 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the Nck2 antibody should be determined by the researcher.
Image Legend
Western blot testing of human 1) SH-SY5Y and 2) ThP1 cell lysate with Nck2 antibody. Predicted molecular weight ~43 kDa.
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