NUDCD3 Antibody / NudC domain-containing protein 3
NudC domain-containing protein 3 is a protein that in humans is encoded by the NUDCD3 gene. The product of this gene functions to maintain the stability of dynein intermediate chain. Depletion of this gene product results in aggregation and degradation of dynein intermediate chain, mislocalization of the dynein complex from kinetochores, spindle microtubules, and spindle poles, and loss of gamma-tubulin from spindle poles. The protein localizes to the Golgi apparatus during interphase, and levels of the protein increase after the G1/S transition.
Product Specifications
CAS Number
9007-83-4
Specifications
UniProt
Q8IVD9
Host
Rabbit
Reactivity
Human
Immunogen
An E.coli-derived human recombinant protein (M1-Y271) was used as the immunogen for the NUDCD3 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, IF, FACS, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
Limitations
This NUDCD3 antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the NUDCD3 antibody should be determined by the researcher.
Location
Cytoplasm
Image Legend
IHC staining of FFPE human placental tissue with NUDCD3 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
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