G-rich sequence factor 1 Antibody / GRSF1
Regulator of post-transcriptional mitochondrial gene expression, required for assembly of the mitochondrial ribosome and for recruitment of mRNA and lncRNA. Binds RNAs containing the 14 base G-rich element. Preferentially binds RNAs transcribed from three contiguous genes on the light strand of mtDNA, the ND6 mRNA, and the long non-coding RNAs for MT-CYB and MT-ND5, each of which contains multiple consensus binding sequences. [UniProt]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000
UniProt
Q12849
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide derived from human GRSF1 protein was used as the immunogen for the G-rich sequence factor 1 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG
Clone
28G51
Type
Recombinant
Applications
WB
Purity
Affinity chromatography
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the G-rich sequence factor 1 antibody at -20oC.
Limitations
This G-rich sequence factor 1 antibody is available for research use only.
Storage Conditions
Store the G-rich sequence factor 1 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the G-rich sequence factor 1 antibody should be determined by the researcher.
Image Legend
Western blot testing of human HEK293 cell lysate with G-rich sequence factor 1 antibody. Predicted molecular weight ~53 kDa.
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