BAG family molecular chaperone regulator 1 Antibody / BAG1

Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70. [UniProt]

Product Specifications

CAS Number

9000-83-3

Specifications

Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:50-1:200, Immunofluorescence: 1:50-1:200

UniProt

Q99933

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide derived from human Bag1 was used as the immunogen for the BAG family molecular chaperone regulator 1 antibody.

Clonality

Recombinant Monoclonal

Isotype

IgG

Clone

28B16

Type

Recombinant

Applications

WB, IHC-P, IF

Purity

Affinity chromatography

Format

Purified

Buffer

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

Reconstitution

Store the BAG family molecular chaperone regulator 1 antibody at -20oC.

Limitations

This BAG family molecular chaperone regulator 1 antibody is available for research use only.

Storage Conditions

Store the BAG family molecular chaperone regulator 1 antibody at -20°C.

Formulation

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

Applications Notes

Optimal dilution of the BAG family molecular chaperone regulator 1 antibody should be determined by the researcher.

Image Legend

Western blot testing of human HeLa cell lysate with BAG family molecular chaperone regulator 1 antibody. Predicted molecular weight ~50 kDa (long form), 29-33 (short form) .