MMACHC Antibody / CblC
Methylmalonic aciduria and homocystinuria type C protein (MMACHC) is a protein that in humans is encoded by the MMACHC gene. The exact function of the protein encoded by this gene is not known, however, its C-terminal region shows similarity to TonB, a bacterial protein involved in energy transduction for cobalamin (vitamin B12) uptake. Hence, it is postulated that this protein may have a role in the binding and intracellular trafficking of cobalamin. Mutations in this gene are associated with methylmalonic aciduria and homocystinuria type cblC.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Flow cytometry: 1-3ug/million cells, ELISA: 0.1-0.5 µg/mL
UniProt
Q9Y4U1
Host
Rabbit
Reactivity
Human
Immunogen
An E.coli-derived human recombinant protein (M1-K242) was used as the immunogen for the MMACHC antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, FACS, ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
Limitations
This MMACHC antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the MMACHC antibody should be determined by the researcher.
Image Legend
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Interleukin 22, Recombinant, Human (IL-22, CRF2–9, IL-TIF R1, IL-10 Related T Cell-derived Inducible Factor) discontinued
Interleukin 22, Recombinant, Human (IL-22, CRF2–9, IL-TIF R1, IL-10 Related T Cell-derived Inducible Factor) discontinued