EYA2 Antibody / Eyes absent homolog 2
Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. [HuProt]
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000
UniProt
O00167
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide derived from human EYA2 was used as the immunogen for the EYA2 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG
Clone
28E31
Type
Recombinant
Applications
WB
Purity
Affinity chromatography
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the EYA2 antibody at -20oC.
Limitations
This EYA2 antibody is available for research use only.
Storage Conditions
Store the EYA2 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the EYA2 antibody should be determined by the researcher.
Image Legend
Western blot testing of human 293T cell lysate with EYA2 antibody. Predicted molecular weight ~59 kDa.
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