Clathrin heavy chain Antibody / CLTC

Clathrin heavy chain 1 is a protein that in humans is encoded by the CLTC gene. Clathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. These specialized organelles are involved in the intracellular trafficking of receptors and endocytosis of a variety of macromolecules. The basic subunit of the clathrin coat is composed of three heavy chains and three light chains.

Product Specifications

CAS Number

9000-83-3

Specifications

Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Immunofluorescence: 5 µg/mL

UniProt

Q00610

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A peptide specific to the human protein was used as the immunogen for the Clathrin heavy chain antibody.

Clonality

Monoclonal

Isotype

IgG

Clone

ABDH-3

Type

Recombinant

Applications

WB, IHC-P, IF

Purity

Antigen affinity purified

Format

Purified

Buffer

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

Reconstitution

Store at -20oC.

Limitations

This Clathrin heavy chain antibody is available for research use only.

Storage Conditions

Store at -20°C.

Formulation

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

Applications Notes

Optimal dilution of the Clathrin heavy chain antibody should be determined by the researcher.

Location

Cytoplasmic

Image Legend

Western blot testing of 1) human HeLa, 2) human 293T, 3) human K562, 4) human PC-3, 5) rat brain, 6) rat kidney, 7) mouse brain and 8) mouse kidney tissue lysate with Clathrin heavy chain antibody. Predicted molecular weight ~192 kDa.