NAPRT Antibody / Nicotinate phosphoribosyltransferase

Nicotinic acid (NA; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT; EC 2.4.2.11) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, Direct ELISA: 0.1-0.5 µg/mL

UniProt

Q6XQN6

Host

Rabbit

Reactivity

Human

Immunogen

E. coli-derived recombinant human protein (amino acids A69-Q480) was used as the immunogen for the NAPRT antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, Direct ELISA

Purity

Antigen affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Reconstitution

After reconstitution, the NAPRT antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This NAPRT antibody is available for research use only.

Storage Conditions

After reconstitution, the NAPRT antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the NAPRT antibody should be determined by the researcher.

Image Legend

Western blot testing of human 1) 293T, 2) HepG2 and 3) HeLa cell lysate with NAPRT antibody. Predicted molecular weight: 56-60 kDa (multiple isoforms) .