PXK Antibody / PX domain-containing protein kinase-like protein

PX domain containing serine/threonine kinase also known as PXK is a protein which in humans is encoded by the PXK gene. This gene encodes a phox (PX) domain-containing protein which may be involved in synaptic transmission and the ligand-induced internalization and degradation of epidermal growth factors. Variations in this gene may be associated with susceptibility to systemic lupus erythematosus (SLE) . Alternative splicing results in multiple transcript variants.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, Immunofluorescence: 5 µg/mL, Direct ELISA: 0.1-0.5 µg/mL

UniProt

Q7Z7A4

Host

Rabbit

Reactivity

Human, Monkey

Immunogen

E. coli-derived recombinant human protein (amino acids E5-K576) was used as the immunogen for the PXK antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IF, Direct ELISA

Purity

Antigen affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Reconstitution

After reconstitution, the PXK antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This PXK antibody is available for research use only.

Storage Conditions

After reconstitution, the PXK antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the PXK antibody should be determined by the researcher.

Location

Cytoplasm, cell membrane

Image Legend

Immunofluorescent staining of FFPE human A549 cells with PXK antibody (red) and DAPI nuclear stain (blue) . HIER: steam section in pH6 citrate buffer for 20 min.