CBP80 Antibody / NCBP1
The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay.
Product Specifications
CAS Number
9007-83-4
Specifications
UniProt
Q09161
Host
Rabbit
Reactivity
Human
Immunogen
E. coli-derived recombinant human protein (amino acids Y121-A790) was used as the immunogen for the CBP80 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, IF, FACS, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
Limitations
This CBP80 antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the CBP80 antibody should be determined by the researcher.
Location
Nuclear, cytoplasmic
Image Legend
IHC staining of FFPE rat hippocampus tissue with CBP80 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
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