PLVAP Antibody / PV-1

Plasmalemma vesicle-associated protein (PLVAP), also called Plasmalemma vesicle protein 1 (PV-1), is a protein that in humans is encoded by the PLVAP gene. Predicted to enable identical protein binding activity. Involved in MAPK cascade; positive regulation of cellular extravasation; and tumor necrosis factor-mediated signaling pathway. Located in cell surface. Colocalizes with caveola. Implicated in congenital diarrhea.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL

UniProt

Q9BX97

Host

Rabbit

Reactivity

Human

Immunogen

E. coli-derived recombinant human protein (amino acids N51-K422) was used as the immunogen for the PLVAP antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, FACS, Direct ELISA

Purity

Antigen affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Reconstitution

After reconstitution, the PLVAP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This PLVAP antibody is available for research use only.

Storage Conditions

After reconstitution, the PLVAP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the PLVAP antibody should be determined by the researcher.

Image Legend

Flow cytometry testing of fixed and permeabilized human HEL cells with PLVAP antibody at 1ug/million cells (blocked with goat sera) ; Red=cells alone, Green=isotype control, Blue= PLVAP antibody.