FGIN 1-43

FGIN 1-43 is an effective and specific ligand for the mitochondrial diazepam binding inhibitor (DBI) receptor (related to the production of neurosteroids) . FGIN 1-43 enhances the transmission of GABA by inducing the production of neurosteroids, which can be used for research on anti-anxiety[1].

Product Specifications

CAS Number

[145040-29-5]

UNSPSC

12352005

Target

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/fgin-1-43.html

Concentration

10mM

Purity

98.96

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(N(CCCCCC)CCCCCC)CC1=C(C2=CC=C(Cl)C=C2)NC3=C1C=C(Cl)C=C3

Molecular Formula

C28H36Cl2N2O

Molecular Weight

487.50

References & Citations

[1]Guillon J, et al. Synthesis and preliminary behavioural evaluation in mice of new 3-aryl-3-pyrrol-1-ylpropanamides, analogues of FGIN-1-27 and FGIN-1-43. J Pharm Pharmacol. 2001 Nov;53 (11) :1561-8.