PDS-0330
PDS-0330 is a specific and potent Claudin-1 inhibitor. PDS-0330 interferes with claudin-1/Src association and inhibits colorectal cancer (CRC) progression and metastasis[1].
Product Specifications
CAS Number
[2904682-19-3]
Product Name Alternative
KVA-E-23A
UNSPSC
12352005
Hazard Statement
H302-H319-H372-H410
Target
Gap Junction Protein
Type
Reference compound
Related Pathways
Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pds-0330.html
Purity
99.77
Solubility
DMSO : 4 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=CC2=C(C=CC=C2)C=C1)NC(NC3=CC=C(C4=NC5=C(O4)C=CC=C5)C=C3)=S
Molecular Formula
C25H17N3O2S
Molecular Weight
423.49
Precautions
P260-P264-P270-P273-P280-P305+P351+P338-P330-P391-P501
References & Citations
[1]Fatima I, et al. Identification and characterization of a first-generation inhibitor of claudin-1 in colon cancer progression and metastasis. Biomed Pharmacother. 2023 Mar;159:114255.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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