DT-6
DT-6 is an effective TGF-β1 inhibitor. DT-6 inhibits M2 macrophage induced epithelial to mesenchymal transition and invasive migration of cancer cells. DT-6 can be used for cancer diseases research[1].
Product Specifications
CAS Number
2414315-95-8
UNSPSC
12352005
Target
TGF-beta/Smad
Type
Reference compound
Related Pathways
Stem Cell/Wnt; TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dt-6.html
Purity
99.82
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C2=C(OCC(NCCCCCC(N[C@@H]([C@H](O)C)C(N[C@@H](CO)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](C)C(N[C@@H](CO)C(N[C@@H]([C@@H](C)CC)C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(N[C@@H](C)C(N[C@@H](CCSC)C(N[C@@H](CCSC)C(N[C@@H](CCC(N)=O)C(N[C@H](C(O)=O)CC(N)=O)=O)=O)=O)=O)=O)CC3=CNC4=CC=CC=C34)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C=CC=C2C(N1C5C(NC(CC5)=O)=O)=O
Molecular Formula
C89H130N20O29S2
Molecular Weight
2008.23
References & Citations
[1]Feng Y, et al. Degradation of intracellular TGF-β1 by PROTACs efficiently reverses M2 macrophage induced malignant pathological events. Chem Commun (Camb) . 2020 Mar 5;56 (19) :2881-2884.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Thyroglobulin (TG) Mouse Monoclonal Antibody [Clone ID: TGB04+TGB05]](https://cdn.genprice.uk/products/937/68dd189e061270361e8fd8bd/imageurl/am50315pu-s.webp)
AM50315PU-S 100 µg
Thyroglobulin (TG) Mouse Monoclonal Antibody [Clone ID: TGB04+TGB05]
Sign In for Pricing
View Details ![INDOL1 (IDO2) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI4H4]](https://cdn.genprice.uk/products/937/68dd1b7d061270361ea1d22f/imageurl/ta806620am.webp)
TA806620AM 100 µL
INDOL1 (IDO2) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI4H4]
Sign In for Pricing
View Details 
BNC040334-100 1x 100 µL
Cytokeratin 8 (H1), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 