Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Mosunetuzumab Biosimilar - Research Grade

Product Specifications

Background

ichorbio’s Mosunetuzumab biosimilar is a bispecific, humanized monoclonal antibody with potential antineoplastic activity. Anti-CD20/CD3 bispecific monoclonal antibody BTCT4465A contains two antigen-recognition sites: one for human CD3, a T-cell surface antigen, and one for human CD20, a tumor-associated antigen (TAA) that is exclusively expressed on B cells during most stages of B-cell development and is often overexpressed in B-cell malignancies. Upon administration, BTCT4465A binds to both T cells and CD20-expressing tumor B cells; this cross-links T cells to tumor cells, and may result in a potent cytotoxic T-lymphocyte (CTL) response against CD20-expressing tumor B cells.

Specifications

Detects human CD3/CD20. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Mosunetuzumab.

Product Name Alternative

BTCT4465A

UniProt

P07766

Species Reactivity

Human

Target

CD3e + CD20

Isotype

IgG1

Applications

Functional Assays

Purification Method

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Concentration

5mg/mL

Endotoxin

≤ 1.0 EU/mg as determined by the LAL method

Purity

>90% by SDS-PAGE

Buffer

ICH3002

Shipping Conditions

Blue ice

Storage Conditions

This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.

Formulation

Sterile, preservative-free, solution in PBS. BSA and Azide free.

Applications Notes

This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.

Isotype Control

https://ichor.bio/product/bulk-human-igg1-isotype-control-ib1-ich2254/

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

HNF6 (ONECUT1) (NM_004498) Human Over-expression Lysate
LC401429 20 µg

HNF6 (ONECUT1) (NM_004498) Human Over-expression Lysate

Sign In for Pricing
View Details
CLEC18B Human Gene Knockout Kit (CRISPR)
KN415966 1 Kit

CLEC18B Human Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
Ɑ-Hydroxy-ω-Squaric Acid Ester Amido PEG
1310000-00-50.1G 1 g

Ɑ-Hydroxy-ω-Squaric Acid Ester Amido PEG

Sign In for Pricing
View Details
LRG1 Rabbit Polyclonal Antibody
TA366224 100 µL

LRG1 Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
BRF1 (Center) Rabbit Polyclonal Antibody
AP50389PU-N 400 µL

BRF1 (Center) Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
N-Carbobenzoxyglycine
TRC-C175995-5G 5 g

N-Carbobenzoxyglycine

Sign In for Pricing
View Details