Mosunetuzumab Biosimilar - Research Grade

Product Specifications

Background

ichorbio’s Mosunetuzumab biosimilar is a bispecific, humanized monoclonal antibody with potential antineoplastic activity. Anti-CD20/CD3 bispecific monoclonal antibody BTCT4465A contains two antigen-recognition sites: one for human CD3, a T-cell surface antigen, and one for human CD20, a tumor-associated antigen (TAA) that is exclusively expressed on B cells during most stages of B-cell development and is often overexpressed in B-cell malignancies. Upon administration, BTCT4465A binds to both T cells and CD20-expressing tumor B cells; this cross-links T cells to tumor cells, and may result in a potent cytotoxic T-lymphocyte (CTL) response against CD20-expressing tumor B cells.

Specifications

Detects human CD3/CD20. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Mosunetuzumab.

Product Name Alternative

BTCT4465A

UniProt

P07766

Species Reactivity

Human

Target

CD3e + CD20

Isotype

IgG1

Applications

Functional Assays

Purification Method

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Concentration

5mg/mL

Endotoxin

≤ 1.0 EU/mg as determined by the LAL method

Purity

>90% by SDS-PAGE

Buffer

ICH3002

Shipping Conditions

Blue ice

Storage Conditions

This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.

Formulation

Sterile, preservative-free, solution in PBS. BSA and Azide free.

Applications Notes

This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.

Isotype Control

https://ichor.bio/product/bulk-human-igg1-isotype-control-ib1-ich2254/

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

YP-W101203-01 48 Tests

Human Ubiquitin Associated Protein 2 (UBAP2) ELISA Kit

Ask

View Details

YP-W101203-02 96 Tests

Human Ubiquitin Associated Protein 2 (UBAP2) ELISA Kit

Ask

View Details

137979-PE 100 µL

FKTN (Fukutin, Fukuyama-type Congenital Muscular Dystrophy Protein, FCMD, CMD1X, LGMD2M, MDDGA4, MDDGB4, MDDGC4, MGC126857, MGC134944, MGC134945, MGC138243) (PE)

Ask

View Details

APR23358N-01 50 µL

KAT5 Rabbit pAb (APR23358N)

Ask

View Details

APR23358N-02 100 µL

KAT5 Rabbit pAb (APR23358N)

Ask

View Details

APR23358N-03 200 µL

KAT5 Rabbit pAb (APR23358N)

Ask

View Details