Girentuximab Biosimilar - Research Grade
Product Specifications
Background
RUO girentuximab binds to the extracellular proteoglycan (PG)-like domain, which is unique to CA IX compared to other isoforms and lies adjacent to the catalytic domain. In addition to therapy, girentuximab has also been utilized as an imaging agent.
Specifications
Detects human Carbonic Anhydrase IX. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Girentuximab Biosimilar - Research Grade.
Product Name Alternative
CAIX, CA-IX
UniProt
Q16790
Species Reactivity
Human
Target
Carbonic Anhydrase IX
Isotype
IgG1
Applications
Functional Assays
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Concentration
5mg/mL
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Buffer
ICH3002
Shipping Conditions
Blue ice
Storage Conditions
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Applications Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Isotype Control
https://ichor.bio/product/bulk-human-igg1-isotype-control-ib1-ich2254/
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