Vedolizumab Biosimilar - Research Grade

Product Specifications

Background

Vedolizumab, an integrin receptor antagonist, is a humanized IgG1 monoclonal antibody produced in Chinese hamster ovary cells that binds to the human α4β7 integrin. Vedolizumab has an approximate molecular weight of 147 kilodaltons.

Specifications

Detects human Integrin alpha 4 + beta 7. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Vedolizumab.

Product Name Alternative

ITGA4, ITGB7

UniProt

P13612

Host

Humanized

Species Reactivity

Human

Target

Integrin alpha 4 + beta 7

Isotype

IgG1

Purification Method

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Concentration

1.0 - 5.0 mg/mL

Endotoxin

≤ 1.0 EU/mg as determined by the LAL method

Purity

>95% by SDS-PAGE and HPLC

Buffer

ICH3001-100mL ICH3002-100mL ICH3003-100mL

Shipping Conditions

Blue ice

Storage Conditions

Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.