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Secukinumab Biosimilar - Research Grade

Product Specifications

Background

Secukinumab is a recombinant human monoclonal IgG1/κ antibody that binds specifically to IL-17A. It is expressed in a recombinant Chinese Hamster Ovary (CHO) cell line. Secukinumab has a molecular mass of approximately 151 kDa; both heavy chains of secukinumab contain oligosaccharide chains.

Specifications

Detects human IL17A. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Secukinumab.

Product Name Alternative

Interleukin-17A, IL17A, CTLA-8, CTLA8

UniProt

Q16552

Host

Humanized

Species Reactivity

Human

Target

IL17A

Purification Method

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Concentration

1.0 - 5.0 mg/mL

Endotoxin

≤ 1.0 EU/mg as determined by the LAL method

Purity

>95% by SDS-PAGE and HPLC

Buffer

ICH3001-100mL ICH3002-100mL ICH3003-100mL

Shipping Conditions

Blue ice

Storage Conditions

Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Product Datasheet

https://ichor.bio/productpdf/print/index/url_key/secukinumab-biosimilar-research-grade/

Formulation

Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.

Isotype Control

https://ichor.bio/product/bulk-human-igg1-isotype-control-ib1-ich2254/

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