Ramucirumab Biosimilar - Research Grade

Product Specifications

Background

Ramucirumab is a recombinant human IgG1 monoclonal antibody that specifically binds to vascular endothelial growth factor receptor 2. ramucirumab has an approximate molecular weight of 147 kDa. ramucirumab is produced in genetically engineered mammalian CHO cells.

Specifications

Detects human VEGFR2. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Ramucirumab.

Product Name Alternative

Vascular endothelial growth factor receptor 2, Kdr, VEGFR-2, Fetal liver kinase 1, FLK-1, Kinase NYK, Protein-tyrosine kinase receptor flk-1, Flk1, CD309

UniProt

P35968

Host

Humanized

Species Reactivity

Human

Target

VEGFR2

Isotype

IgG1

Purification Method

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Concentration

1.0 - 5.0 mg/mL

Endotoxin

≤ 1.0 EU/mg as determined by the LAL method

Purity

>95% by SDS-PAGE and HPLC

Buffer

ICH3001-100mL ICH3002-100mL ICH3003-100mL

Shipping Conditions

Blue ice

Storage Conditions

Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.