Ramucirumab Biosimilar - Research Grade
Product Specifications
Background
Ramucirumab is a recombinant human IgG1 monoclonal antibody that specifically binds to vascular endothelial growth factor receptor 2. ramucirumab has an approximate molecular weight of 147 kDa. ramucirumab is produced in genetically engineered mammalian CHO cells.
Specifications
Detects human VEGFR2. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Ramucirumab.
Product Name Alternative
Vascular endothelial growth factor receptor 2, Kdr, VEGFR-2, Fetal liver kinase 1, FLK-1, Kinase NYK, Protein-tyrosine kinase receptor flk-1, Flk1, CD309
UniProt
P35968
Host
Humanized
Species Reactivity
Human
Target
VEGFR2
Isotype
IgG1
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Concentration
1.0 - 5.0 mg/mL
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE and HPLC
Buffer
ICH3001-100mL ICH3002-100mL ICH3003-100mL
Shipping Conditions
Blue ice
Storage Conditions
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Formulation
Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.
Isotype Control
https://ichor.bio/product/bulk-human-igg1-isotype-control-ib1-ich2254/
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