Calcein AM (Highly Pure)

<strong>Calcein AM (Highly Pure)</strong>_x000D_ <strong>Catalog number:</strong> B2011099_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 994.9 g/mol_x000D_ <strong>Supplied as:</strong> Lyophilized_x000D_ <strong>Applications:</strong> molecular tool for various chemical, biochemical and immunological applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> Calcein-AM, Calcein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Uggeri J, Gatti R, Belletti S, Scandroglio R, Corradini R, Rotoli BM, Orlandini G. Calcein-AM is a detector of intracellular oxidative activity Histochem Cell Biol. 2004 Nov;122(5):499-505._x000D_ 2: Jonsson B, Liminga G, Csoka K, Fridborg H, Dhar S, Nygren P, Larsson R. Cytotoxic activity of calcein acetoxymethyl ester (Calcein/AM) on primary cultures of human haematological and solid tumours Eur J Cancer. 1996 May;32A(5):883-7._x000D_ 3: Iwanowicz LR, Densmore CL, Ottinger CA. Calcein AM release-based cytotoxic cell assay for fish leucocytes Fish Shellfish Immunol. 2004 Feb;16(2):127-37._x000D_ 4: Dolma S, Lessnick SL, Hahn WC, Stockwell BR. Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells Cancer Cell. 2003 Mar;3(3):285-96._x000D_ 5: Tawakoli PN, Al-Ahmad A, Hoth-Hannig W, Hannig M, Hannig C. Comparison of different live/dead stainings for detection and quantification of adherent microorganisms in the initial oral biofilm Clin Oral Investig. 2013 Apr;17(3):841-50._x000D_ 6: Chan LL, McCulley KJ, Kessel SL. Assessment of Cell Viability with Single-, Dual-, and Multi-Staining Methods Using Image Cytometry Methods Mol Biol. 2017;1601:27-41._x000D_ 7: Tenopoulou M, Kurz T, Doulias PT, Galaris D, Brunk UT. Does the calcein_AM method assay the total cellular 'labile iron pool' or only a fraction of it? Biochem J. 2007 Apr 15;403(2):261-6._x000D_ 8: Lv Y, Liu R, Xie S, Zheng X, Mao J, Cai Y, Chen W. Calcein-acetoxymethy ester enhances the antitumor effects of doxorubicin in nonsmall cell lung cancer by regulating the TopBP1/p53RR pathway Anticancer Drugs. 2017 Sep;28(8):861-868._x000D_ 9: Bratosin D, Mitrofan L, Palii C, Estaquier J, Montreuil J. Novel fluorescence assay using calcein-AM for the determination of human erythrocyte viability and aging Cytometry A. 2005 Jul;66(1):78-84._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/10500791">10: Legrand O, Simonin G, Perrot JY, Zittoun R, Marie JP. Both Pgp and MRP1 activities using calcein-AM contribute to drug resistance in AML Adv Exp Med Biol. 1999;457:161-75. </a>_x000D_ _x000D_ <strong>Products Related to Calcein AM (Highly Pure) can be found at</strong> <a href="https://moleculardepot.com/product-category/Chemicals/"> Chemicals</a>