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Anti-Mouse CD90.1 (OX-7) In Vivo Antibody - Ultra-Low Endotoxin

Product Specifications

Background

CD90 has been found to play a role in numerous cellular activities, such as cell adhesion, apoptosis, metastasis, inflammation, and fibrosis. In mouse strains expressing CD90.1, it is expressed on early-stage hematopoietic cells in bone marrow, thymocytes, and circulating mature T cells. The OX-7 antibody has been reported to induce leukocyte activation, glomerular nephritis, apoptosis in glomerular mesangial cells, and vascular permeability. CD90 can be used as a marker for a variety of stem cells and for the axonal processes of mature neurons. Diseases associated with CD90 dysfunction include nasopharyngeal carcinoma and thymoma.

Specifications

Clone OX-7 activity is directed against both rat and murine CD90/Thy-1.

Host

Mouse

Species Reactivity

Mouse,Rat

Target

CD90.1

Isotype

IgG1

Clone

OX-7

Applications

Depletion, Flow Cytometry, Immunofluorescence, Immunohistochemistry

Purification Method

This monoclonal antibody was purified using Protein A

Concentration

≥ 2.0 mg/mL

Endotoxin

≤ 0.5 EU/mg as determined by the LAL method

Purity

>98% by SDS-PAGE and HPLC

Buffer

ICH3001-100mL ICH3002-100mL ICH3003-100mL

Shipping Conditions

Blue ice

Storage Conditions

This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Product Datasheet

https://ichor.bio/productpdf/print/index/url_key/anti-mouse-cd90-1-ox-7-in-vivo-antibody-low-endotoxin/

Formulation

Sterile, preservative-free, solution in PBS. BSA and Azide free.

Antigen Distribution

CD90 is present on a variety of cell types in murine and rat, including lymphatic vessels, T cells, neurons and fibroblasts

Aggregation

Aggregation level ≤ 1%

Applications Notes

Each investigator should determine their own optimal working dilution for specific applications.

Isotype Control

https://ichor.bio/product/mouse-igg1-isotype-control-for-in-vivo-low-endotoxin-hksp84-ich2248/

CAS Number

9007-83-4

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