Bulk Anti-Human CD1d (D5) Antibody
Product Specifications
Background
CD1d antibody, D5, recognizes human CD1d, also known as CD1.1 and Ly-38, a 48 kDa type 1 membrane glycoprotein that belongs to the cluster of differentiation 1 (CD1) family of glycoproteins. CD1d is expressed on epithelial cells and monocyte-derived antigen presenting cells (APCs), including monocytes, DCs, and macrophages. CD1d is an MHC class I-like molecule involved in the presentation of lipid antigens, such as α-galactosylceramide (α-GalCer), to a highly conserved T cell subset, named invariant natural killer T (iNKT) cells or CD1d-restricted T cells1. Following activation, iNKT cells rapidly proliferate and produce large amounts of cytokines and cytolytic mediators
Specifications
Clone D5 recognizes an epitope on human CD1d
Product Name Alternative
R3G1
UniProt
P15813
Host
Mouse
Species Reactivity
Human
Target
CD1d
Isotype
IgG2b
Clone
D5
Applications
Immunoprecipitation, Western Blot
Purification Method
This monoclonal antibody was purified using Protein A
Concentration
≥ 5.0 mg/mL
Endotoxin
<1.0 EU/mg as determined by the LAL method
Purity
≥95% monomer by analytical SEC, >95% by SDS Page
Buffer
ICH3001-100mL ICH3002-100mL ICH3003-100mL
Shipping Conditions
Blue ice
Storage Conditions
This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Product Datasheet
https://ichor.bio/productpdf/print/index/url_key/bulk-anti-human-cd1d-d5-antibody/
Formulation
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added.
Antigen Distribution
CD1d is expressed on monocytes, DCs, macrophages, and epithelial cells
Aggregation
Aggregation level ≤ 5%
Isotype Control
https://www.ichor.bio/product/Mouse-IgG2b-Isotype-Control-for-In-Vivo-Low-Endotoxin-MPC-11-ICH2250
CAS Number
9007-83-4
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