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Bulk Anti-Human CD64 (10.1) Antibody

Product Specifications

Background

Fc gamma receptors (FcγRs) are membrane-bound proteins which control and mediate communication of IgG antibodies within the immune system. These receptors play a crucial role in the link between the innate and adaptive immune system. FcγRI, CD64, is expressed on dendritic cells, macrophages/monocytes, and granulocytes. Of the FcγRs, FcγRI is capable of interacting with monomeric IgG with relatively high affinity.

CAS Number

9007-83-4

Specifications

Clone 10.1 recognizes an epitope on human Fc��RI

Product Name Alternative

Fc-gamma receptor 1, FcγRI, Fc Gamma Receptor Ia, Fc-Gamma RIA, CD64

UniProt

P12314

Host

Mouse

Species Reactivity

Human

Target

CD64

Isotype

IgG1 Kappa

Clone

10.1

Applications

Blocking, Functional Assays, Flow Cytometry, Immunofluorescence, IHC (Frozen), Immunoprecipitation

Purification Method

This monoclonal antibody was purified using Protein A

Concentration

>2.0 mg/mL

Endotoxin

≤ 1.0 EU/mg as determined by the LAL method

Purity

>95% by SDS-PAGE and HPLC

Buffer

ICH3001-100mL ICH3002-100mL ICH3003-100mL

Shipping Conditions

Blue ice

Storage Conditions

This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Formulation

This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2 – 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and azide free

Antigen Distribution

FcγRI (CD64) is an IgG receptor expressed by monocytes and myeloid cell lines.

Aggregation

Aggregation level ≤ 5%

Applications Notes

Each investigator should determine their own optimal working dilution for specific applications.

Isotype Control

https://www.ichor.bio/product/Mouse-IgG1-Isotype-Control-for-In-Vivo-Low-Endotoxin-HKSP-ICH2247

Frequently Asked Questions

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