Anti-Mouse TNFR2 (TR75-54.7) In Vivo Antibody - Low Endotoxin
Selected Variant
ICH1137-25mg
Size: 25 mg
Product Specifications
Background
Tumor necrosis factor receptor II (TNF-RII) is present on most cell types and is considered to play a prominent role in stimulation by TNF-alpha. TNFRII proteins are expressed by hematopoietic cells including macrophages, neutrophils, lymphocytes, thymocytes and mast cells. It is expressed by a variety of other cell types including endothelial cells, cardiac myocytes and prostate cells
CAS Number
9007-83-4
Specifications
Anti-TNFR2 In Vivo Antibody - Low Endotoxin (TR75-54.7) recognizes Mouse CD120
Product Name Alternative
Tnfrsf1b, Tumor necrosis factor receptor superfamily member 1B, Tumor necrosis factor receptor 2, TNF-R2, Tumor necrosis factor receptor type II, TNF-RII, TNFR-II, p75, p80 TNF-alpha receptor, CD120b, Tnfr-2
UniProt
P25119
Host
Armenian Hamster
Species Reactivity
Mouse
Target
TNFR2
Isotype
IgG
Clone
TR75-54.7
Applications
Immunoprecipitation, Western Blot, Blocking, Flow Cytometry, ELISA
Purification Method
This monoclonal antibody was purified using Protein A
Concentration
1.0 mg/mL
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE and HPLC
Buffer
ICH3001-100mL ICH3002-100mL ICH3003-100mL
Shipping Conditions
Blue ice
Storage Conditions
Anti-TNFR2 In Vivo Antibody - Low Endotoxin (TR75-54.7) is stable for at least four (4) weeks when stored sterile at 2-8°C. For long-term storage aseptically aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Formulation
0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Aggregation
Aggregation level ≤ 5%
Applications Notes
Blocking: Clone TR75-54.7 antibody has been reported to block ligand-induced receptor signaling.
Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control
https://www.ichor.bio/product/Armenian-Hamster-IgG-Isotype-Control-for-In-Vivo-Low-Endotoxin-PIP-ICH2251
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