Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-Mouse TNF Alpha (TN3-19.12) In Vivo Antibody - Ultra-Low Endotoxin

Product Specifications

Background

The tumor necrosis factor (TNF-alpha) is a multifaceted polypeptide cytokine known as a mediator of inflammation and immunity. It may mediate some of the significant changes in cellular homeostasis which accompany the invasion of the mammalian host by viruses, bacteria, and parasites. TNF-alpha is an acute phase protein which initiates a cascade of cytokines and increases vascular permeability, thereby recruiting macrophage and neutrophils to a site of infection. TNF-alpha secreted by the macrophage causes blood clotting which serves to contain the infection. TNF-alpha has been detected in synovial fluid of patients with rheumatoid arthritis. Clone TN3-19.12 antibody can neutralize the bioactivity of natural or recombinant TNF-alpha

Specifications

Anti-TNF alpha In Vivo Antibody - Ultra Low Endotoxin (TN3-19.12 ) recognizes Mouse TNFa

Product Name Alternative

Cachectin, TNFa, Tumor necrosis factor ligand superfamily member 2, Tnfsf2

UniProt

P06804

Host

Armenian Hamster

Species Reactivity

Mouse

Target

TNF alpha

Isotype

IgG

Clone

TN3-19.12

Applications

Immunoprecipitation, Western Blot, Functional Assays, Flow Cytometry, Blocking

Purification Method

This monoclonal antibody was purified using Protein A

Concentration

≥ 2.0 mg/mL

Endotoxin

≤ 0.5 EU/mg as determined by the LAL method

Purity

>98% by SDS-PAGE and HPLC

Buffer

ICH3001-100mL ICH3002-100mL ICH3003-100mL

Shipping Conditions

Blue ice

Storage Conditions

Anti-TNF alpha In Vivo Antibody - Ultra Low Endotoxin (TN3-19.12 ) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

Product Datasheet

https://ichor.bio/productpdf/print/index/url_key/Anti-TNF-alpha-In-Vivo-Antibody-Low-Endotoxin-TN3-19.12-ICH1136/

Formulation

0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.

Antigen Distribution

Activated monocytes, neutrophils, macrophages, T cells, B cells, NK cells, LAK cells

Aggregation

Aggregation level ≤ 1%

Applications Notes

Each investigator should determine their own optimal working dilution for specific applications.

Isotype Control

https://www.ichor.bio/product/Armenian-Hamster-IgG-Isotype-Control-for-In-Vivo-Low-Endotoxin-PIP-ICH2251

CAS Number

9007-83-4

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Calbindin D28K Rabbit pAb
E2251640 100 µL

Calbindin D28K Rabbit pAb

Ask
View Details
TMEM14B Adenovirus (Human)
46908052 1.0 ml

TMEM14B Adenovirus (Human)

Ask
View Details
Anti-EBF1 Antibody (8E567)
TMAB-05414-01 25 µL

Anti-EBF1 Antibody (8E567)

Ask
View Details
Anti-EBF1 Antibody (8E567)
TMAB-05414-02 50 µL

Anti-EBF1 Antibody (8E567)

Ask
View Details
Anti-EBF1 Antibody (8E567)
TMAB-05414-03 100 µL

Anti-EBF1 Antibody (8E567)

Ask
View Details
GRAMD4 Polyclonal Antibody
MBS9235785-01 0.1 mL

GRAMD4 Polyclonal Antibody

Ask
View Details