A-350619 (hydrochloride)

A-350619 hydrochloride is a soluble guanylate cyclase (sGC) activator. A-350619 hydrochloride can be used in the study of erectile dysfunction[1][2].

Product Specifications

CAS Number

[1217201-17-6]

UNSPSC

12352005

Target

Guanylate Cyclase

Type

Reference compound

Related Pathways

GPCR/G Protein

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/a-350619-hydrochloride.html

Purity

96.36

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(NCCCCN(C)C)/C=C/C1=C(SC2=CC=C(C=C2)Cl)C=CC=C1.Cl

Molecular Formula

C21H26Cl2N2OS

Molecular Weight

425.41

References & Citations

[1]Kotzki S, et al. Anodal iontophoresis of a soluble guanylate cyclase stimulator induces a sustained increase in skin blood flow in rats. J Pharmacol Exp Ther. 2013 Sep;346 (3) :424-31.|[2]Miller LN, et al. A-350619: a novel activator of soluble guanylyl cyclase. Life Sci. 2003 Jan 17;72 (9) :1015-25.