Antibacterial agent 212

Antibacterial agent 212 (Compound 162) is an antibacterial agent with oral activity and good pharmacokinetic properties, having a MIC of 4 μg/mL against Pseudomonas aeruginosa T-2022-D2-048[1].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antibacterial-agent-212.html

Solubility

10 mM in DMSO

Smiles

CC1=C(C=NC(C2=CC=C(C=C2)CSSC(C)(C)C)=N1)C(N[C@H](C(N([C@@H]3C(N[C@H](C(N[C@@H](CC4=CC=C(C(C5=C(C=CC3=C5)OCCN)=C4)OCCN)C(NCC#N)=O)=O)C)=O)C)=O)CCN)=O

Molecular Formula

C48H61N11O7S2

Molecular Weight

968.20

References & Citations

[1]Zhang Y, et al. Design, Synthesis, and Biological Evaluation of Novel Arylomycins against Multidrug-Resistant Gram-Negative Bacteria. J Med Chem. 2024;67 (8) :6585-6609.