N-Caffeoyldopamine

N-Caffeoyldopamine (Compound 6i) is an amyloid-beta aggregation inhibitor. N-Caffeoyldopamine can inhibit Aβ aggregation to form nano-rod-like structures, thereby preventing β-sheet formation. N-Caffeoyldopamine can be used for Alzheimer's disease research[1].

Product Specifications

UNSPSC

12352005

Target

Amyloid-β

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/aβ-in-9.html

Purity

90.00

Smiles

OC1=C(O)C=CC(CCNC(/C=C/C2=CC(O)=C(O)C=C2)=O)=C1

Molecular Formula

C17H17NO5

Molecular Weight

315.32

References & Citations

[1]Xu F, et al. Synthesis and evaluation of catecholamine derivatives as amyloid-beta aggregation inhibitors. Bioorg Med Chem Lett. 2024 Jul 15;107:129788.