SSAA09E3

SSAA09E3 is a SARS-CoV entry inhibitor that inhibits SARS/HIV pseudotyped virus entry with an EC50 of 9.7 μM in 293T cells and inhibits SARS-CoV infection of Vero cells with an EC50 of 0.15 μM[1][2].

Product Specifications

CAS Number

[52869-18-8]

UNSPSC

12352005

Hazard Statement

H302, H319, H372, H410

Target

SARS-CoV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/ssaa09e3.html

Purity

99.42

Solubility

DMSO : 33.33 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(NC(C=C1C2=O)=CC=C1C(C3=C2C=CC=C3)=O)C4=CC=CC=C4

Molecular Formula

C21H13NO3

Molecular Weight

327.33

Precautions

H302, H319, H372, H410

References & Citations

[1]Ghosh AK, et al. Drug Development and Medicinal Chemistry Efforts toward SARS-Coronavirus and Covid-19 Therapeutics. ChemMedChem. 2020 Jun 4;15 (11) :907-932.|[2]Adedeji AO, et al. Novel inhibitors of severe acute respiratory syndrome coronavirus entry that act by three distinct mechanisms. J Virol. 2013 Jul;87 (14) :8017-28.