BMY-25551

BMY-25551 is a Mitomycin A (HY-130332) analogue that is 8 to 20 times more potent than Mitomycin C (HY-13316) in cytotoxicity to murine and human tumor cell lines. BMY-25551 can be utilized in cancer and hematologic depression research[1].

Product Specifications

CAS Number

[105139-98-8]

UNSPSC

12352005

Target

Drug Derivative; Macrophage migration inhibitory factor (MIF)

Type

Reference compound

Related Pathways

Immunology/Inflammation; Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bmy-25551.html

Smiles

CO[C@]12N(C[C@@]3([H])[C@]2([H])N3)C4=C(C(C(OCCO)=C(C4=O)C)=O)[C@H]1COC(N)=O

Molecular Formula

C17H21N3O7

Molecular Weight

379.36

References & Citations

[1]Bradner WT, et al. Experimental tumor inhibitory and toxic properties of the mitomycin A analogue 7- (2-hydroxyethoxy) mitosane (BMY-25551) . Anticancer Res. 1992 May-Jun;12 (3) :959-64.