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Hydroxy-PEG4-C2-methyl ester

Hydroxy-PEG4-C2-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

[2228857-35-8]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/hydroxy-peg4-c2-methyl-ester.html

Purity

97.89

Solubility

10 mM in DMSO

Smiles

O=C(OC)CCOCCOCCOCCOCCO

Molecular Formula

C12H24O7

Molecular Weight

280.31

Precautions

H302, H315, H319, H335

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Alkyl/ether Linkers; PEG Linkers

Available Sizes

Curated Selection

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