4-Acetylbenzoic acid

4-Acetylbenzoic acid is a Zn (II) complex. 4-Acetylbenzoic acid is a derivative of benzoic acid that is commonly used in chemical synthesis. 4-Acetylbenzoic acid has an IC50 of 331.3 μM in murine L929 fibroblasts and an IC50 of 176 μM in metastatic melanoma B16 F10 cell lines[1][2][3].

Product Specifications

CAS Number

[586-89-0]

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/4-acetylbenzoic-acid.html

Concentration

10mM

Purity

99.76

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

O=C(O)C1=CC=C(C(C)=O)C=C1

Molecular Formula

C9H8O3

Molecular Weight

164.16

Precautions

H302, H315, H319, H335

References & Citations

[1]Nakamura R, et al. Selective oxidation of acetophenones bearing various functional groups to benzoic acid derivatives with molecular oxygen[J]. Advanced Synthesis & Catalysis, 2009, 351 (10) : 1677-1684.|[2]Wang L H, et al. Synthesis, Structural Characterization, DFT, Hirschfeld Surface and Catalytic Activity of a New Zn (II) Complex of 4-Acetylbenzoic Acid[J]. Bulletin of Chemical Reaction Engineering & Catalysis, 2023, 18 (2) : 200-209.|[3]Islam, A., et al., (2016) . Cytotoxicity and apoptotic activity of novel organobismuth (V) and organoantimony (V) complexes in different cancer cell lines. European journal of medicinal chemistry, 109, 254–267.