L-Histidine

L-Histidine is an essential amino acid for infants. L-Histidine is an inhibitor of mitochondrial glutamine transport.

Product Specifications

CAS Number

[71-00-1]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; Mitochondrial Metabolism

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Metabolic Disease; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/L-Hisidine.html

Purity

99.97

Solubility

DMSO : < 1 mg/mL|H2O : 20.83 mg/mL (ultrasonic; warming; heat to 80°C)

Smiles

N[C@@H](CC1=CNC=N1)C(O)=O

Molecular Formula

C6H9N3O2

Molecular Weight

155.16

Precautions

H302, H315, H319, H335

References & Citations

[1]Bou Zeidan M, et al. L-histidine inhibits biofilm formation and FLO11-associated phenotypes in Saccharomyces cerevisiae flor yeasts. PLoS One. 2014 Nov 4;9 (11) :e112141.|[2]Rama Rao KV, et al. Brain edema in acute liver failure: inhibition by L-histidine. Am J Pathol. 2010 Mar;176 (3) :1400-8.|[3]Yoshikawa T, et al. Insufficient intake of L-histidine reduces brain histamine and causes anxiety-like behaviors in male mice. J Nutr. 2014 Oct;144 (10) :1637-41.