Ranitidine S-oxide
Ranitidine S-oxide is the metabolite of Ranitidine (HY-B0693) . Ranitidine is a potent, selective and orally active histamine H2-receptor antagonist with an IC50 of 3.3 μM that inhibits gastric secretion[1][2].
Product Specifications
CAS Number
[73851-70-4]
UNSPSC
12352005
Hazard Statement
H317, H334, H335
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ranitidine-s-oxide.html
Purity
99.03
Solubility
H2O : 125 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=[N+](/C=C(NCCS(CC1=CC=C(CN(C)C)O1)=O)\NC)[O-]
Molecular Formula
C13H22N4O4S
Molecular Weight
330.41
Precautions
H317, H334, H335
References & Citations
[1]Cross DM, et al. Kinetics of ranitidine metabolism in dog and rat isolated hepatocytes. Xenobiotica. 1995 Apr;25 (4) :367-75.|[2]Leucuta A, et al. A pharmacokinetic interaction study between omeprazole and the H2-receptor antagonist ranitidine. Drug Metabol Drug Interact. 2004;20 (4) :273-81.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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