Rabbit anti Human Lass3
Product Specifications
Background
LASS3 (Longevity Assurance homolog 3) is a member of a highly conserved family of proteins from yeast to Humans which are involved in the synthesis of ceramide. Overproduction of LASS3 appears to results in increases in several ceramide species, with some preference toward those having middle to long chain fatty acid acyl-CoAs. Also appears to have (dihydro)ceramide synthesis activity. LASS3 expression appears to be limited almost solely to the testis.
CAS Number
9007-83-4
Synonyms
LAG1 longevity assurance homolog 3
UniProt
Q8IU89
Host
Rabbit
Species Reactivity
Human
Conjugation
Affinity Purified
Type
Antigen Immunoaffinity Purified Polyclonal
Applications
WB
Purification Method
Antigen Immunoaffiinity Purification
Assay Principle
Antibody can be used for Western blotting (1:400 starting dilution). Optimal concentration should be evaluated by serial dilutions.
Stability
See expiration date on vial
Concentration
Lot specific, See vial
Form
Provided as a solution in Tris buffered saline with 0,08% sodium azide, 10mM MgCl2, 10mM ammonium sulfate, and 0,2% lactose.
Precautions
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving Humans or animals.
References & Citations
Mizutani, Y., et al. 'LASS3 (longevity assurance homologue 3) is a mainly testis-specific (dihydro)ceramide synthase with relatively broad substrate specificity.' Biochem. J., 2006, 398, 531-538.
Shipping Conditions
Ambient Temperature, freeze upon arrival
Storage Conditions
Product should be stored at -20ºC; Aliquot to avoid freeze/thaw cycles
Functional Analysis
WB
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