(+) -Amosulalol
(+) -Amosulalol ((+) -YM 09538) is an isomer of Amosulalol , an orally active dual inhibitor of α1/β1-adrenergic receptors. Amosulalol exhibits antihypertensive activity by inhibiting α1-adrenergic receptors. Amosulalol reduces the reflex increase in heart rate and plasma renin activity (PRA) in spontaneously hypertensive rats (SHR) by inhibiting β1-adrenergic receptors.
Product Specifications
CAS Number
94666-17-8
Product Name Alternative
(+) -YM 09538
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/plus-amosulalol.html
Smiles
O=S(C1=CC([C@H](O)CNCCOC2=CC=CC=C2OC)=CC=C1C)(N)=O
Molecular Formula
C18H24N2O5S
Molecular Weight
380.46
References & Citations
[1]Pharmacokinetics and metabolism of an alpha, beta-blocker, amosulalol hydrochloride, in mice: biliary excretion of carbamoyl glucuronide
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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