GSDMD Antibody / Gasdermin D

Gasdermin D is a precursor of a pore-forming protein that plays a key role in host defense against pathogen infection and danger signals. [UniProt]

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Immunofluorescence (FFPE) : 5 µg/mL, Flow cytometry: 1-3ug/million cells

UniProt

P57764

Host

Mouse

Reactivity

Human

Immunogen

E. coli-derived recombinant human protein (amino acids M1-H484) was used as the immunogen for the GSDMD antibody.

Clonality

Monoclonal

Isotype

IgG2b

Clone

6D11

Applications

WB, IHC-P, IF, FACS

Purity

Antigen affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Reconstitution

After reconstitution, the GSDMD antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This GSDMD antibody is available for research use only.

Storage Conditions

After reconstitution, the GSDMD antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the GSDMD antibody should be determined by the researcher.

Location

Nucleus, cytoplasm, cell membrane, secreted

Image Legend

Immunofluorescent staining of FFPE human PC-3 cells with GSDMD antibody (green) and DAPI nuclear stain (blue) . HIER: steam section in pH6 citrate buffer for 20 min.

Documents

Product Datasheet

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