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SULF2 Antibody / Extracellular sulfatase Sulf-2

Extracellular sulfatase Sulf-2 is an enzyme that in humans is encoded by the SULF2 gene. Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, Direct ELISA: 0.1-0.5 µg/mL

UniProt

Q8IWU5

Host

Rabbit

Reactivity

Human

Immunogen

E. coli-derived recombinant human protein (amino acids K471-D614) was used as the immunogen for the SULF2 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, Direct ELISA

Purity

Antigen affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Reconstitution

After reconstitution, the SULF2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This SULF2 antibody is available for research use only.

Storage Conditions

After reconstitution, the SULF2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the SULF2 antibody should be determined by the researcher.

Image Legend

Western blot testing of human 1) MCF7 and 2) HepG2 cell lysate with SULF2 antibody. Predicted molecular weight ~100 kDa but may be observed at higher molecular weights due to glycosylation.

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