GSDMD Antibody / Gasdermin D
Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL
UniProt
P57764
Host
Mouse
Reactivity
Human
Immunogen
E. coli-derived recombinant human protein (amino acids M1-H484) was used as the immunogen for the GSDMD antibody.
Clonality
Monoclonal
Isotype
IgG2a
Clone
3D5
Applications
WB, IHC-P
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
Limitations
This GSDMD antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the GSDMD antibody should be determined by the researcher.
Location
Nucleus, cytoplasm, cell membrane, secreted
Image Legend
IHC staining of FFPE human lymph node tissue with GSDMD antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items