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GSDMD Antibody / Gasdermin D

Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL

UniProt

P57764

Host

Mouse

Reactivity

Human

Immunogen

E. coli-derived recombinant human protein (amino acids M1-H484) was used as the immunogen for the GSDMD antibody.

Clonality

Monoclonal

Isotype

IgG2a

Clone

3D5

Applications

WB, IHC-P

Purity

Antigen affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Reconstitution

After reconstitution, the GSDMD antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This GSDMD antibody is available for research use only.

Storage Conditions

After reconstitution, the GSDMD antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the GSDMD antibody should be determined by the researcher.

Location

Nucleus, cytoplasm, cell membrane, secreted

Image Legend

IHC staining of FFPE human lymph node tissue with GSDMD antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

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