Thrombomodulin Antibody / THBD
The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia.
Product Specifications
CAS Number
9007-83-4
Specifications
UniProt
P07204
Host
Rabbit
Reactivity
Human, Rat
Immunogen
E. coli-derived recombinant human protein (amino acids Q29-L575) was used as the immunogen for the Thrombomodulin antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, IF, FACS, IP, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
Limitations
This Thrombomodulin antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Thrombomodulin antibody should be determined by the researcher.
Location
Cell surface, cytoplasm, nucleus
Image Legend
Documents
Frequently Asked Questions
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